Carboxytherapy can dramatically improve the appearance of dark under-eye circles. Although sometimes caused by darkened pigment, or a hollow depression below the lower eyelids [tear trough deformity], the majority of dark under-eye circles are caused by poor circulation beneath the lower eyelids [vascular pooling]. Dr. Zdinak designed and conducted the first study in the English literature using carboxytherapy for rejuvenating the under- eye region. Carboxytherapy